What types of enzymes play a catalytic role in the regulation pathway of ubiquitination?

Answers

Answer 1

Answer:

ubiquitin activating enzyme ( E1), a ubiquitin conjugating enzyme (E2), and a ubiquitin ligase (E3).

Explanation:

In ubiquitination, ubiquitin (regulatory protein) attach to a protein to inactivate it and targets a protein for degradation via the proteasome.

There are three enzymes sequentially catalyse the process of ubiquitination that includes ubiquitin activating enzyme ( E1), a ubiquitin conjugating enzyme (E2), and a ubiquitin ligase (E3).

The E1 activates ubiquitin by forming a thiol ester bond between the C terminus of ubiquitin and the active cysteine of the E1 which is an ATP dependent step.

The activated ubiquitin then tranferred to cysteine of E2 which along with E3 transfers the ubiquitin to a lysine residue in the target protein.

Hence, all three ubiquitin activating enzyme ( E1), a ubiquitin conjugating enzyme (E2), and a ubiquitin ligase (E3) enzymes sequentially catalyse the process of ubiquitination.


Related Questions

Do Now: b) Complete the following mRNA Strand: GCATACAGT (Be sure to look if it is asking for DNA or mRNA. DNA is GCAT and mRNA is GCAU. All answers must be in capitals when writing out bases, or the will be considered wrong.)

Answers

Answer:

CGUAUGUCA

Explanation:

Firstly, the strand in the question is a DNA strand because it contains the Thymine base, which is only found in a DNA molecule. The process of changing a DNA molecule into RNA molecule (specifically a messenger RNA) is called transcription. Transcription is done using the complementary base pairing rule, which states that Adenine (A) will always pair with Thymine (T), and Guanine (G) will always pair with Cytosine (C).

In the case of transcription, the Thymine bases will change to Uracil (U), since Uracil is only found in the RNA molecule. That is, A-U and G-C. Hence, a DNA strand that reads: GCATACAGT will produce a mRNA strand CGUAUGUCA.

A health researcher was interested in finding out whether the DASH diet can lower a dieter’s blood pressure. Researchers compared the blood pressure before going on the diet with the same subject’s blood pressure after 12 weeks on the DASH diet. Which of the following is the most appropriate statistical test to use to test whether the DASH diet lowers blood pressure?

A) Matched pairs t-testB) Inference for regressionC) ANOVAD) Chi-squared test for independenceE) Two-sample t-test

Answers

Answer:

a matched pairs t-test

--PLEASE HELP--

What is the population density if there are 40 squirrels in 4 square miles?

Answers

Answer:

10 squirrels/ square mile

Explanation:

Population density can be found by dividing the number of individuals by the area of the land they live in.

population/ land area

We want to find the population density for 40 squirrels that live in 4 square miles. Therefore, the population is 40 squirrels and the area of the land is 4 square miles.

population / land area

40 squirrel/ 4 square miles

Divide 40 by 4

40/4=10

10 squirrels/ square mile

The population density is 10 squirrels per square mile.

Which is one of the six fundamental elements that are found in living organisms?

Answers

Answer:

1: Carbon

2: Hydrogen

3: Nitrogen

4: Oxygen

5: Phosphorus

6: Sulfur

Explanation:

The six fundamental elements that are found in living organisms are carbon, hydrogen, nitrogen, oxygen, phosphorus, and sulfur.

Hope this helps.

A patient is receiving an infusion of an IV medication. The IV bag contains 800 ml of the solution, which is infusing at 100 cc/hr. If the infusion started at 2 pm, when will it finish?

Answers

Answer: 10 pm

Explanation: 800 ml infusing at 100cc/hr would take 8hrs so 8 hrs from 2pm is 10pm

Which best describes the process of peer review ?

Answers

You basically just review the work of your peer as in somebody else’s work and they do the same for you !

Answer:

Scientists examine each other's work often to make sure it is not biased or unreliable. this makes for a group effort and reliable information.NOT JUST SCIENCE

Many fields outside of science use peer review to ensure quality.

Explanations : Peer review is the process of peers in the field of the work review the work and give opinion of it

With respect to mammalian cell culture, which of the following statements is true? During the establishment of a cell line, senescence is the last stage of the cell's life. Rodent cells cultures undergo spontaneous transformation with similar frequency to human cell cultures. Media used for cell growth contain proteases and a divalent cation chelator to help cells adhere to the surface. Embryonic cell lines do not undergo senescence nor do they have a finite life span.

Answers

Answer:

Media used for cell growth contain proteases and a divalent cation chelator to help cells adhere to the surface.

Explanation:

Mammalian cell structure is the process where animals cells are grow in vitro in a flask or dish. The methods, equipments, reagents and supplies use in this type of culture prevent contamination and maintain cell culture purity. Protein enzymes like Serine protease breaks the cellular matrics interaction between the cells. In cell culture, the focal adhesions that are anchoring the cell to the culture dish is cut away. Most trypsin solutions for cell culture also contain EDTA which acts as a chelator for calcium. When calcium is remove from a solution, cadehrin that hold cells to each other break down and cells become separated from each other.

Which descriptions apply to these two compounds? Check all that apply.

are isomers of each other

have same molecular formula

have same structural formula

are both hydrocarbons

have same number of each kind of atom

have same geometric arrangement of atoms

Answers

Image is not provided in the question. The required image is attached below.

Answer:

A. are isomers of each other

B. have same molecular formula

D. are both hydrocarbons

E. have same number of each kind of atom

Explanation:

The two given compounds are 3- methylpentane and 2,2 - Dimethylbutane.

They both are isomers with the same molecular formula C6H14. They both are made up of carbon and hydrogen called hydrocarbons.

As they have same molecular formula C6H14, so they have same number of each kind of atom including carbon and hydrogen.

Hence, the correct options are:

A.

B.

D.

E.

Answer:

a

b

d

e

Explanation:

How many individuals show the trait being followed?

Correct answer gets brainlest

Answers

Answer: 8 carry the trait and 2 show the trait

Explanation: the halves are the carriers and the full ones are those who show the trait

The optical microscope is regularly used to identify bacteria and viruses. In 1918 the Spanish Flu infected almost one third of the world and was thought to be caused by bacteria. However, a virulent virus was the cause of the Spanish Flu. From what we have learned throughout this lab on microscopy, why weren't scientists able to identify the Spanish Flu with a microscope?

Answers

Answer:

In 1918, one of the deadliest pandemics in history took place, known as the Spanish flu. The flu infected almost 500 million individuals globally, that is, about 33 percent of the world's population. Due to the Spanish flu, the death of about 20 to 50 million people took place.  

The general symptoms of the first wave of Spanish flu were fever, chills, and fatigue. However, during the second wave, the people started to die within hours after the development of the signs, due to the development of a fluid taking place within the lungs resulting in suffocation.  

At the time of the Spanish flu pandemic, not much was known regarding the composition of the virus. The scientists at that time were not able to make a difference between a bacteria and a virus. This made it tough for scientists to determine the Spanish flu with the help of a microscope.  

What is the mean of the data set [3,2,2,12,6,5,14,4]?

A.2
B.4
C.6
D.7

Answers

Answer:

6

Explanation:

To find the mean of a data set, add all the values in the set together, and then divide the result by the number of values in the set.

3 + 2 + 2 + 12 + 6 + 5 + 14 + 4 = 48

There are 8 values in the data set.

48/8 = 6

So the mean of the data set is 6.

Can someone please help me

Answers

Answer:

Explanation:

Department of Transportation because they are in charge of regulating the safe travel and shipment of materials

Answer:

Department of Transportation

Explanation:

launchpad A Drosophila mutation called singed (s) causes the bristles to be bent and misshapen. A mutation called purple (p) causes the fly’s eyes to be purple in color instead of the normal red. Flies homozygous for singed and purple were crossed with flies that were homozygous for normal bristles and red eyes. The F1 were intercrossed to produce the F2, and the following results were obtained. What are the genotypes of the parental flies in Cross 1

Answers

Answer:

ppss and PPSS

Explanation:

Just as indicated in the question above, Flies homozygous for singed and purple were crossed with flies that were homozygous for normal bristles and red eyes.

And a Drosophila mutation called singed (s) causes the bristles to be bent and misshapen.

A mutation called purple (p) causes the fly’s eyes to be purple in color instead of the normal red.

Thus, the genotypes of the parental flies in Cross 1 are

PPSS and ppss

Maja's family has a history of heart disease. What can she do to help lower her chance of having heart disease?

Answers

Improving her diet and environmental factors. Exercise and have a healthy life

what part of the nervous system controls your internal organs

Answers

Answer:

autonomic nervous system

Explanation: that can control everything in our body

Answer:

The central nervous system (CNS) controls most functions of the body and mind. It consists of two parts: the brain and the spinal cord.

HOPE IT HELPS :)

PLEASE MARK IT THE BRAINLIEST!

Which is a key component of the energy molecule ATP?

Answers

Answer:

The correct answer is phosphorous but occurs in the form of a phosphate

What is the disease called that increases your age with extreme progression?

Answers

Answer:

werner syndrome

Explanation:

Werner syndrome is a rare progressive disorder that is characterized by the appearance of unusually accelerated aging (progeria). Although the disorder is typically recognized by the third or fourth decades of life, certain characteristic findings are present beginning during adolescence and early adulthood.

hope it helps please mark me brainliest xD

Answer:

ur mum

Explanation:

Naval writes out the chemical equation for photosynthesis. She includes two reacting molecules to the left of the arrow and two resulting molecules to the right.
Light energy, above the arrow
Chlorophyll,to the left of the arrow
Enzymes, to the left of the arrow
ATP, above the arrow

Answers

Answer:

The question is incomplete. The remaining fragment that completes the question is: "What more must be added to the chemical equation to accurately represent photosynthesis? "

The answer is Light energy, above the arrow

Explanation:

Photosynthesis is a metabolic reaction unique to autotrophic organisms like plants, algae etc. It is the process whereby these organisms produce their food (glucose) using light energy from the sun.

Photosynthesis cannot occur without light, as the name implies: Photo- meaning light. The sun is the source of this light energy, which photosynthetic organisms like plants capture using a green pigment called CHLOROPHYLL.

Photosynthesis is a reaction with a general equation:

6CO2 + 6H2O ---light energy-----> C6H12O6 + 6O2

However, the energy needed to perform this reaction comes from light provided by the sun. Hence, Naval needs to put LIGHT above the arrow in her equation in order to accurately represent photosynthesis.

Which of the following can cause acid precipitation?
A. The use of solar panels
B. The use of Hydroelectricity
C. The use of coal
D. All of the above

Answers

Answer:

C. The use of coal

Explanation:

Poisons and salts are removed from the blood by the _____.
lungs
stomach
kidneys
skin

Answers

Answer:

Kidneys

Explanation:

The kidneys remove wastes and excess water in the body through the urine, as urine flows from the kidneys to the bladder through two thin tubes located on both sides of the bladder called the ureter, and the bladder stores urine, and each of the kidneys consists of about one million filtering units called the renal tubular unit contains Each renal tubular unit has a filter called the glomerulus and tubule, and the renal tubular unit operates through a two-step process:

glomerulus: filters blood.  

Tubule: Returns the necessary substances to the blood and removes waste.

AnswEr:

Kidneys

Explanation:

I hope dis helps :D

Which helps prevent errors in DNA replication?
A. DNA is produced in the ribosomes.
B. There are no complementary base pairs in DNA.
C. DNA polymerase checks the DNA for errors.
D. DNA polymerase makes five DNA molecules from each single
strand, and keeps the best of the five.

Answers

DNA polymerase checks the DNA for errors and there are no complementary base pairs in DNA (Options B and C). It helps to prevent errors during DNA replication.

What is DNA replication?

DNA replication refers to the cellular process aimed at generating two identical molecules of DNA during cell division.

DNA replication is a fundamental mechanism to sure the perpetuity of genetic material (i.e., the inheritance of genetic material).

During DNA replication, most DNA polymerases check the DNA for errors, repairing errors in a mechanism known as DNA proofreading.

Learn more about DNA replication here:

https://brainly.com/question/21265857

Both archaea and bacteria have a/n _______, but it is made of peptidoglycan in bacteria and pseudo peptidoglycan in archaea.

Answers

Answer: Cell Wall

Explanation: Both archaea and bacteria have a/n Cell Wall, but it is made of peptidoglycan in bacteria and pseudo peptidoglycan in archaea.

You are a pharmaceutical researcher trying to design a new drug for the treatment of cystic fibrosis. You are aware that an extracellular protein that is a chloride ion transporter is misfolded and never gets to the cell surface. You have a new undergraduate working with you. Explain which organelle is involved in this process and why the transporter protein is nonfunctional.

Answers

Answer:

Endoplasmic reticulum is the defective organelle in most CF.

Explanation:

This is because of  mutation(deletion) in the proteins of these organelle. The CFTR  protein -a transmembrane regulator get stucked inside the E.R, thus  the  CFTR chloride protein channel is blocked. Therefore the outflow of Cl and water  out of the cell  is obstructed.

Consequently, the mucus from blocked fluid flow, clogs the lungs, the fallopian tube, sweat duct, and other places.

This nutrient is cycled between living things and the soil. Plants absorb this nutrient from the soil and turn it into organic compounds through assimilation. Animals eats the plants and pass the nutrient through the food chain from one organism to another. When the animal dies, it decomposes and returns the nutrient back to the soil. The nutrient can also enter the soil through weathering and erosion.

Answers

Answer:

1. Phosphorus cycle

2. Carbon cycle

3. Nitrogen cycle

Explanation:

Answer:

1. Phosphorus

2. Carbon Cycle

3. Nitrogen Cycle

Explanation:

1. Plant hormones include the following
except.
A. insulin
B. auxin
C. cytokinin
D. gibberellin​

Answers

A. Insulin as it is a human hormone produced in the pancreas to the liver....

Hope this helps ya

Answer:

insulin

Explanation:

it is a hormone found in humans.

abi you barb

If you follow the longest food chain in the food web below from grass to owl,
how many trophic levels are there?
grass
aspen
grasshopper
rabbit-fox
frog
#snake
owl
o
A. Three
B. Five
C. Four
D. Two

Answers

Answer:

I believe the correct answer is B. Five

3 Question
Select the correct answer.
Which of these is a component of the atmosphere?
rock
oxygen
sediments
soil

Answers

Answer:

oxygen

Explanation:

Which of the following statements is correct regarding chromosomes?
A. Chromosomes are strands of DNA, tightly wrapped up, that are located in the nucleus.
B. Chromosomes are strands of RNA, tightly wrapped up, that are in the cytoplasm.
C. Chromosomes are strands of RNA, loosely wrapped up, that are located everywhere in the cell.
D. Chromosomes are strands of DNA, tightly wrapped up, that are located everywhere in the cell.

Answers

Answer:

A. Chromosomes are strands of DNA, tightly wrapped up, that are located in the nucleus.

Explanation:

Hope this helped and pls mark me brainliest

The statement that says "Chromosomes are strands of DNA, tightly wrapped up, that are located in the nucleus" is correct regarding chromosomes.

Chromosomes are the highly organized structures inside biological cells, made up of DNA and other proteins, and where most of an individual's genetic information resides.

Chromosomes have a double structure, composed of two structures parallel to each other and joined by a centromere, called chromatids.

In eukaryotic cells (with a defined nucleus), the chromosomes are elongated and found in the nucleus, while in prokaryotic cells, such as bacteria, these appear as circular rings closed in the nucleoid.

The chromosome allows the DNA information to be conserved and evenly distributed.

Therefore, we can conclude that chromosomes are condensed strands or rings of DNA and are located in the nucleus of cells when they are not dividing.

Learn more about chromosomes here: https://brainly.com/question/12463363

Antibiotics can be highly effective in treating bacterial infections, as long as the bacteria have not developed _______ to the antibiotics.
Bacteria or viruses can cause _______ diseases, which are increasing in occurrences, geographic area, or both.

Answers

Answer: Immunity

Explanation: Antibiotics can be highly effective in treating bacterial infections, as long as the bacteria have not developed immunity to the antibiotics.

A antibiotic that block protein synthesis and have broad spectrum
activities with relatively low toxicity is:

A. bacitracin
B. penicillin
C. vancomycin
D. erythromycin
E. levofloxacin

Answers

D hope this helps brother
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Why is Jon Daltons discovery important to science? Help please A manufacturing company preparing to build a new plant is considering three potential locations for it. The fixed and variable costs for the three alternative locations are presented below.a. complete a numeric locational cost-volume analysisb. Indicate over what range each of the alternatives A, B, C is the low-cost choicec. Is any alternative never perferred? ExplainCost A B CFixed ($) 2,500,000 2,000,000 3,500,000Vaiable ($ per unit) 21 25 15 ANSWER ASAPP!!! EASYYY!! choose the correct correspondence. Line B A) R B) S C)T Which stage of the heros journey is represented in this passage?This was an army, trained to fight on horsebackor, where the ground required, on foot. They camewith dawn over that terrain like the leavesand blades of spring. So doom appeared to us,dark word of Zeus for us, our evil days.My men stood up and made a fight of itbacked on the ships, with lances kept in play,from bright morning through the blaze of noonso holding our beach, although so far outnumbered;but when the sun passed toward unyoking time,then the Achaeans, one by one, gave way.A. The return homeB. The road of trails C.The transformation D.The call to adventure What is history? In your own words explain. Can facing obstacles ever be a positive experience? How does facing adversity define, or shape a person? what would be the answer for this. Number 2 is the one that needs to be answered Question:Train A arrives at the station at 11:50 AM and leaves the station at 1:50 PM. How long does it stay in the station?Make a Selection:A.1 hrB.2 hrsC.1 hr 25 minD.10 hrs Plz help asap, dhdhhsbdhd The long a sound can be heard in which of the following spelling words?receiveneighborsleighreceipt Please I need help with this ASAp...Thanks and will give you brainlist... Researchers are working to develop biofuels to free us from dependence on fossil fuels. Based on what you know about cellulose, what do you predict are the major advantage and disadvantage of using cellulose-rich plant material as biofuel? you invested $22,000 in two accounts paying 4% and 9% annual interest. if the total interest earned for the year was $1180, how much was invested at each rate can someone give me 10-20 facts about laughter and how it helps.. pls answer this asap!! ______ ______ are created when something is caused to vibrate. Suppose you catch and hold a baseball, and then someone invites you to catch and hold a bowling ball with either the same momentum or the same kinetic energy as the baseball. Which would you choose what makes The Importance of Being Earnest a comedy of manners